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 Tamoxifen and Raloxifene 8/99
 Canadian Analysis Finds No Improved Survival Raloxifene:Benefits versus Risks Benefit Greatest to Prevent Hormone-Dependent Bca
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 NCI Bulletin, 12/06

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 Am Assoc for Cancer Research,
4/03
 Press Release: Tam Effective at Lower Doses 2 Years Vs. 5 Years for Early Bca Age 50+
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 February 2001, Switzerland
Includes basic info on the BCPT1

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 A Comparison of Prices
with some LINKS to Canadian
pharmacies

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 Perspective and summary from
Sharon Batt, a Canadian activist
 Ann Fonfa's Testimony to the FDA 9/2/98 Washington Post Coverage, 9/98
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 Journal, The Breast
February 2001
 Canada: Net Health Impact of Tamoxifen
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 November 3, 1999
JNCI article
 Study: Tamoxifen & Uterine Tumors Tamoxifen Eligibility:PREVENTION in White Women Tamoxifen Useful for Women 40-50 with 3.4% Five-Year Risk
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 Federation of European
Cancer Societies 3/02

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 Another study demonstrates
NOT helpful in Stage 1 ER-.

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 Helen Schiff's passionate
presentation on Tamoxifen
for healthy women, 6/00
 Questions and Answers on Tamoxifen
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 Barbara Seaman and Ann Fonfa
also sign on to release

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 Written by Carol Hochberg and Ann Fonfa

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 Study, The Lancet
11/00

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 An article by Andrea Martin,
Exec. Dir. The Breast Cancer Fund
 Effect of Raloxifene on Bca Cell Ki67 and Apoptosis Tam, Raloxifene Show Preclinical Cross-resistance
|  |  |  | 
 Cancer Letter 2000.
early study results
 Tamoxifen for Five Years GLA and Tamoxifen May Down-Regulate ER Pathway Black Cohosh & No Proliferation of Bca Cells Tamoxifen Plus Soy Prevents Bca in Rats Melatonin & Tamoxifen Good Combo IP6 Enhances Adriamycin & Tamoxifen (Bca) EPA Restores Tamoxifen Sensitivity (Akt activity) Flaxseed Enhances Inhibitory Effect of Tamoxifen: ER+ Bca
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 Journal-The Breast,
April 2001
 Adverse Effects Not Properly Recorded Tamoxifen & Depression Toxicity of Antiestrogens Tamoxifen Controversy-Negative Effects Verbal Memory Impaired with Hormonal Therapy Changes in Serum Triglycerides w/Tam Gallstones Linked to Tamoxifen Use: Postmenopausal Coagulation Behavior With Adj Post-op Tamoxifen C-erb B2 Decreases Benefit of Adj Tam Venous Thrombosis BCa Tamox/Chemo: Review Tamoxifen w/Radiotherapy: CAUTION for Radiosensitive Pts
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 Lancet, December 2000
 Most Women with Family Hist DO NOT Get Bca Tamoxifen and BRCA Mutations Estimates of Prophylactic Effects of Tamoxifen *BRCA1&2) Breast Cancer Prevention-UK Study Breast Gel Version of Tamoxifen Tamoxifen/Chemoprevent/BRCA1/2:Docs Recommendations
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 Canadian Medical Association Journal,
June 2001
 Britain's Dept of Health Says No to Tamoxifen in Healthy Women
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 JNCI,7/01
 Author Musa Mayer Remarks on this Study AP's Take:ER negative tumors develop After Tam Use DNA Methylation Prfle Predicts Recurrence Risk:Tam/BCa Benefits/Risk Tamoxifen Similar White & Black Women
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 Breast Cancer Res Treat, 2001

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 Jpn J of Clinical Oncology, 12/01
 Tamoxifen's Effectiveness & Slow version of a Gene
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 1/16/02 Reuters and
FDA Website

|  |  |  | 
 JAMA, 1/02
 Cross-Resistance Tam Vs. Ralox
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 The Oncologist, 2/02
 Risk/Benefit in Int'l Intervention Study Update on Royal Marsden Tamoxifen Prevention Trial
|  |  |  | 
 Peter D'Adamo, ND
perspective, 2001
 Use of Adjv Chemo in ATAC Trial-Nationality Correlates
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 Intl J Cancer, 4/02
 Age/Body Mass Affects Dose
|  |  |  | 
 Cancer Information Service Reports
on ASCO 2002 presentation
 Uterine Sarcoma Risk Advocate Letter to FDA on Warning Labels, 2002 Risk Maliganant Mixed Mullerian Tumors *(Uterine)
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 Some advice, information, and tips
But mostly you must make your own
informed decision

|  |  |  | 
 Annals of Internal Medicine, 7/02
VERY IMPORTANT INFORMATION

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 Oncogene, 7/02

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 Presented at Dept of Defense
Breast Cancer Res Conference, 9/02

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 JNCI, 2/03

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 Press Release, JNCI
3/03

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 Tumori, 3-4/02

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 Univ of Maryland, 5/03

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 JNCI, 12/03

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 #A193
Frontiers in Cancer Prevention Res, 2003

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 SABCS, 12/03
 Tamoxifen has Little Impact on Mortality
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